Tumour-derived exosomes (TDEs) were also shown by Hosseini et al. (2021) to carry several bioactive molecules (HLA-G, COX-2, PGE2, TGF-β, IL-6, HSP70, HSP72) that can interfere with the maturation of DCs, thus decreasing their capability in inducing effective anti-tumour responses. This evidence concerns the gene HLA-G and neoplasm.