After backward stepwise regression analysis, children with double the levels of cat and Aspergillus IgE had an elevated risk of current asthma (aOR, 1.12; 95% CI, 1.02 to 1.24 for cats and aOR, 1.19; 95% CI, 1.08 to 1.33 for Aspergillus) (Table 4). This evidence concerns the gene IGHE and asthma.