Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are ideal for patients with overweight T2DM because they control blood glucose and promote weight loss.[7,8] Liraglutide is a representative medication effectively used to treat overweight T2DM patients and has a low risk of hypoglycemia.[9]. The gene discussed is GLP1R; the disease is type 2 diabetes mellitus.