Its biosynthesis is controlled by two main factors: angiotensin II (Ang II) and extracellular potassium concentration (K+).[3,4] Unilateral primary aldosteronism (UPA) is mainly caused by aldosteronogenic adenomas, due to the mutations in potassium and calcium channels or ion pumps. Here, AGT is linked to urokinase-type plasminogen activator measurement.