The Mayo Clinic reported 637 patients with GPA from 1996 to 2011 and thought that neither the Birmingham vasculitis score nor the GPA injury index could be used to assess the occurrence and severity of GPA-H.[15] In this study, ESR was not high in three of the nine patients, and CRP was not high in two of the nine patients. The gene discussed is CRP; the disease is granulomatosis with polyangiitis.