AFP and neoplasm: It may correlate to defect of primary tumor capsular[5] or capsular rupture during operation.[6] In addition, genetic evidence has demonstrated they have unique genetic characteristics.[7,8] The IMCT along with many serum tumor markers increased, for example, carbohydrate antigen 125 (CA125)[4,9] and α-fetoprotein (AFP).[10,11] However, no studies have reported that an elevated level of serum human chorionic gonadotrophin (HCG) is associated with IMCT or GP so far.