We found scattered reactive particles of both HIV (red) and KSHV (green) in the tumor cells of most HIV + KS samples (23/24, 95.8%, Fig. 3, Table S1, Supplemental Digital Content 2, http://links.lww.com/MD/H758) according to cell morphology along with positive CD34 staining. The gene discussed is CD34; the disease is neoplasm.