TGFBR2 and acute respiratory distress syndrome: [108] reported that EV miR-145 level was significantly decreased in blood samples of an LPS-induced mouse model of ALI, similar to the results from sepsis patients; and intravenous injection of a miR-145 agomir into this mouse model, before or after LPS treatment, could attenuate lung inflammation and injury by attenuating TGFBR2 signaling.