There is a correlation between the high expression of key genes involved in autophagic processes such as SIRT1 (sirtuin 1), BECN1 (beclin 1), STK11/LKB1 (serine/threonine kinase 11), and ATG7 (autophagy-related 7) and poor clinical outcome, short remission duration and drug resistance in patients with AML [50, 51]. This evidence concerns the gene STK11 and acute myeloid leukemia.