Recently Lemoine M et al. reported that the gamma-glutamyl transpeptidase (GGT) to platelet ratio (GPR) can predict significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa [2], which can be used in other populations and hepatitis B virus-related liver cancer [3–7]. This evidence concerns the gene GGTLC1 and Hepatic fibrosis.