TP53 and cancer: To support these findings, A11 showed minimal effects on the migratory- and filopodia-forming potential of cancer cells expressing DNA-contact mutp53 (MDA-MB-231: p53R280K, FaDu: p53R248L, HSC4: p53R248Q), wtp53 (SJSA1, U2OS, HCT116 p53+/+), and p53 null (MG63, HCT116 p53−/−, H1299) (Supplementary Fig. 4B, C).