SQSTM1 and lung adenocarcinoma: In A549 xenografts, CUR5g administration markedly promoted LC3B-II and SQSTM1 levels by immunofluorescence staining and western blot analysis, confirming the efficiency of CUR5g in inhibiting autophagy of lung adenocarcinoma in vivo. However, whether there is a link between CUR5g-induced S phase arrest and autophagy inhibition remains unknown.