CDH1 and CDH7 were highly expressed in luminal A cell lines; CDH5 was mostly expressed in human epidermal growth factor receptor-2 (HER2) cell lines; CDH2/3/4/6/11/12/13/15/18/19/22/23 showed high expressions in multiple triple-negative breast cancer cell lines; and other CDH genes showed no specific expressions in molecular subtypes of breast cancer cell lines. The gene discussed is CDH5; the disease is breast cancer.