For CDH4, BPs demonstrated correlations with proteasomal protein catabolic process; the CC analysis showed correlations with the mitochondrial inner membrane and mitochondrial matrix; MFs revealed significant relationships with actin binding and ion channel activity, while KEGG ontology indicated the role of pathways of multiple neurodegenerative diseases (Supplementary Figure 11A). Here, CDH4 is linked to neurodegenerative disease.