Interestingly, ALS-FP had a skew towards down-regulation (46 ncRNA transcripts down-regulated vs 15 ncRNA transcripts up-regulated) in comparison to the more balanced dysregulation in the ALS-SP groups (down-regulated: 45; up-regulated: 43), and between the ALS-SP and ALS-FP groups (down-regulated: 60; up-regulated: 52). This evidence concerns the gene TFF2 and amyotrophic lateral sclerosis.