TP53 and neoplasm: As expected, oroxylin A treatment upregulated p53 level and key proteins of p53 signalling including cleaved‐caspase‐3, cleaved‐caspase‐9, and Bax while downregulated Bcl‐2 in HepG2 cells, HepG2 xenograft tumours, and DEN‐induced liver tumours (Figure 4G,H; Figure S4D).