Only when miR223 was overexpressed in both innate immune lineages was the tumor incidence fully rescued, with a similar percentage of fish displaying tailfin melanomas to those of control Ras;WT fish (Tg(kita:HRASG12V‐GFP;lyz:TagRFP;mpeg1:eGFP);WT) without miR223 overexpression (Figure 1J). This evidence concerns the gene LYZ and melanoma.