LCP1 and neoplasm: To determine whether anti‐miR223 PCs could change the phenotype of leukocytes in the tumor within the vicinity of the injection area, we injected tailfin melanomas of Ras‐expressing adult fish (Tg(kita:HRASG12V‐GFP)) with PCs loaded with either scrambled‐anti‐miR (control) or anti‐miR223 cargo, dissected the tumor, and immunostained sections of these tumors with anti‐L‐plastin and anti‐IL1β antibodies at several timepoints post injection.