These showed a potential efficacy in predicting AKI: the AUC were 0.872 (95% CI 0.732–0.974) for ESM1 (Figure 4A), 0.917 (95%CI: 0.778–1.000) for EHBP1L1(Figure 4B), 0.949 (95%CI: 0.826–1.000) for FBXW4 (Figure 4C), 0.970 (95%CI: 0.912–1.000) for MDFI (Figure 4D), 0.974 (95%CI: 0.923–1.000) for MDM4 (Figure 4E), and 0.886 (95%CI: 0.786–0.974) for RALYL (Figure 4F). The gene discussed is MDM4; the disease is acute kidney injury.