BAG2 and Huntington disease: Furthermore, the IPA signaling pathway analysis revealed that Huntington’s disease (p = 1.88 ⋅10–8), mitochondrial dysfunction (p = 3.81 ⋅10–7), oxidative phosphorylation (p = 1.07 ⋅10–6), BAG2 signaling pathway (p = 1.20 ⋅10–5), and the sirtuin signaling pathway (p = 1.25 ⋅10–4) are the most affected canonical pathways in the CDR2-treated retinal explants (see Table 3).