Data analysis visualized by representative images of the four groups (Figure 2B) and the compiled results (Figure 2C) demonstrated that healthy women and men showed no difference in the IL-10-secreting cell fraction while women with obesity and T2D had significantly higher proportion of IL-10-secreting macrophages compared to all other examined groups (Figure 2C). The gene discussed is IL10; the disease is obesity due to melanocortin 4 receptor deficiency.