PRL and hyperprolactinemia: Nevertheless, the positive correlation between the log-transformed PRL and Lp(a) in OLZ-treated patients, which has not been reported in any previous study to the best of our knowledge, indicates that increased cardiovascular risk in OLZ-treated patients with hyperprolactinemia should be the focus of research in this context, especially in males (5), as Lp(a) is an independent marker of cardiovascular risk (67).