Carney Complex is caused by germline mutations in PRKAR1A (which encodes the PKA regulatory RIα subunit) and, rarely, PRKACA or PRKACB [which encode the PKA catalytic subunits Cα or Cβ, respectively, Figures 1, 2, refs (94–96)]. The gene discussed is PRKAR1A; the disease is Carney complex.