TP53 and central nervous system cancer: The KEGG pathway enrichment analysis showed that the 23 DEGs were enriched in the HIF-1 signaling pathway, FoxO signaling pathway, bladder cancer, JAK-STAT signaling pathway, endometrial cancer, renal cell carcinoma, p53 signaling pathway, melanoma, non-small cell lung cancer, and glioma (Figure 3B).