DARA is a humanized IgG1κ monoclonal antibody(mAb) that specifically binds to the epitopes of the cell surface of CD38, directly killing tumor cells through immune-mediated cytotoxicity, such as ADCC, CDC, and ADCP, and inducing apoptosis via FCγ receptor-mediated cross-linking (45–50). This evidence concerns the gene CD38 and neoplasm.