Indeed, the cell surface CD38 density of seven AML cell lines (HL-60, U-937, THP-1, MOLM-13, UOC-M1, Oci-AML2, and KasUMI-1) was detected, with CD38 levels ranging from very high (UOC-M1, 46.5 ± 4.9), high (OCI-AML2, 16.6 ± 1.5), low (THP-1, 7.0 ± 0.2), very low (molm-13, 2.1 ± 1.0 and Kasumi-1, 1.1 ± 1.2), to CD38-negative (HL-60, U-937). This evidence concerns the gene CD38 and acute myeloid leukemia.