CD38 and neoplasm: Akin to other mAbs, CD38 antibodies inhibit tumor cell growth through complement-dependent cytotoxicity (CDC) (41, 45–47), antibody-dependent cytotoxicity (ADCC) (41, 45, 46), and antibody-dependent macrophage phagocytosis (ADCP) (48, 49) and induce apoptosis (45, 50).