In summary, patients with HPV infection (12, 46, 60), SCC (60), advanced stage (46, 60), large tumor size (61), poorly differentiated tumors (61), metastatic tumors (60), history of multiple parity and abortion (57), and a previous history of receiving chemotherapy (46) tend to have a higher expression of PD-L1, though more evidence is still needed. The gene discussed is CD274; the disease is metastatic neoplasm.