Whereas the gene expressions of ATP7A, SLC25A3, SCO2, COA6, TMEM199, ATP6AP1, LIPT1, DLAT, PDHA1, MTF1, ACP1, FDX2, NUBP2, CIAPIN1, ISCA2, and NDOR1 in HCC tissues were prominently higher than their surrounding tissues, and the differences were all statistically significant (P < 0.001, Figure 2). This evidence concerns the gene FDX2 and hepatocellular carcinoma.