The BZM induced apoptosis in the tumor cells with the high expression of Bax (a marker of apoptosis) in both groups of rats with and without music impact (96.32 ± 7.33% vs. 1.57 ± 0.07%, p<0.001 for the GBM+BZM+Music and 64.12 ± 3.31% vs. 1.57 ± 0.07%, p<0.001 for the GBM+BZM, the Mann–Whitney–Wilcoxon test, n=7 in each group). Here, BAX is linked to neoplasm.