FGL2 and central nervous system cancer: And we also found that FGL2 mRNA expression levels were higher in high-grade gliomas than in low-grade gliomas, and low expression of FGL2 increased patient survival and prolonged patient survival time based on the Chinese Glioma Genome Atlas (CGGA) (http://www.cgga.org.cn/) and the Cancer Genome Atlas (TCGA)(http://cancergenome.nih.gov/) databases.(Figure 1) These data suggest that FGL2 expression in glioma is positively correlated with tumor malignancy and patient survival.