Moreover, it has been proved that Zinc-finger E-box binding homeobox 1 (ZEB1) could induce upregulation of LBX2-AS1 to enhance the stability of ZEB1 and ZEB2, which could promote the migration and mesenchymal transformation of esophageal squamous cell carcinoma (22). Here, LBX2 is linked to esophageal squamous cell carcinoma.