Moreover, it has been proved that Zinc-finger E-box binding homeobox 1 (ZEB1) could induce upregulation of LBX2-AS1 to enhance the stability of ZEB1 and ZEB2, which could promote the migration and mesenchymal transformation of esophageal squamous cell carcinoma (22). This evidence concerns the gene ZEB2 and esophageal squamous cell carcinoma.