After Univariate Cox regression, 31 genes including AANAT, ASMT, CBS, CBSL, CKM, CSAD, HAO1, IL4L1, NNMT, PSAT1, PSMB10, PYCR1, RPL13, RPL18, RPL22L1, RPL27A, RPL28, RPL35, RPL36, RPL36A, RPL37, RPLP0, RPS19, RPS2, RPS20, RPS8, SLC45A2, SLC5A5, SLC6A7, TDO2, and UROC1 demonstrated worse prognosis, while the other 26 genes were correlated with better outcomes in ccRCC patients (Figure 2E). The gene discussed is RPL22L1; the disease is nonpapillary renal cell carcinoma.