CCS and lung cancer: In the circ-CCS/miR-383/E2F7 axis, upregulation of circ-RNA copper chaperone for superoxide dismutase (circ-CCS is also called circ_0092306) and E2F transcription factor 7 (E2F7) along with miR-383 downregulation in lung cancer tissues have all been shown to be related to advanced tumor stage and unfavorable prognosis (Yuan et al., 2021).