In the circ-CCS/miR-383/E2F7 axis, upregulation of circ-RNA copper chaperone for superoxide dismutase (circ-CCS is also called circ_0092306) and E2F transcription factor 7 (E2F7) along with miR-383 downregulation in lung cancer tissues have all been shown to be related to advanced tumor stage and unfavorable prognosis (Yuan et al., 2021). This evidence concerns the gene E2F7 and lung cancer.