FLVCR2 and low grade glioma: FLVCR2 expression increased in tumors, such as renal papillary cell carcinoma, renal clear cell carcinoma, and low-grade glioma (LGG), compared to that in matched healthy samples (Figure 6A), and FLVCR2 downregulation predicted the dismal OS for 518 LGG cases (Figure 6B).