Interestingly, ASPC3 was uniquely enriched for COL1A1, COL6A1, FN1, LOX, and LUM, which are fibrosis markers recently associated with a specific subset of PDGFRA+ progenitor cells in murine model of obesity (Marcelin et al., 2017). Here, COL1A1 is linked to obesity due to melanocortin 4 receptor deficiency.