It is interesting to note that haplotype analysis of the three polymorphisms evaluated showed that in the presence of the rs5743618 polymorphism, the T allele (TLR1 602I) does not seem to interfere in defining the risk/protection to the development of leprosy since it is the allele change in the TLR2 gene that shows a difference in the association with the disease, that is, when the T allele of the TLR1 gene is present if the C allele of TLR2 (rs4696483) is present, the haplotype formed suggests a risk of developing leprosy. Here, TLR1 is linked to leprosy.