In addition, genes such as SRSF1, BUB1B, KIF23, and HNRNPF also play an important role in breast cancer, but so far, there is few reports on the association between these genes and the treatment or prognosis of breast cancer in the previous studies (Tyson-Capper and Gautrey, 2018; Du et al., 2021; Jian et al., 2021; Koyuncu et al., 2021); inspiringly, we performed it and obtained an exact result in our study. This evidence concerns the gene HNRNPF and breast cancer.