CD8A and nonpapillary renal cell carcinoma: Patients with higher levels of Tex, natural regulatory T cell (nTreg), Th1, effector memory T cell (Tem), and CD8+ T cell had notably worse OS, while high infiltrating levels of Th2, Tcm, and gamma delta T cell (Tgd) predicted better prognosis in ccRCC patients (Figure 4).