C1QTNF6 and hepatocellular carcinoma: Among these, CTRP3, CTRP4, CTRP6, and CTRP8 have been reported to be strongly associated with several malignant tumors, like osteosarcoma (Akiyama et al., 2009), hepatocellular carcinoma (Wan et al., 2019), glioblastoma (Glogowska et al., 2022), and other malignancies (Kong et al., 2021).