Although no ideal animal model has been established that fully recapitulates the human features of dry AMD, both the PEG-400 model (Lygozubov et al., 2014) and the chemokine ligand 2 (CCL2) knock out (KO) model (Ambati et al., 2003) share certain common characteristics with dry AMD. Here, CCL2 is linked to dry age related macular degeneration.