For example, Fan et al. demonstrated that ginseng diol inhibited proliferation and induced apoptosis of pancreatic cancer cell lines PANC-1 and Patu8988 through the JAK2/STAT3 signaling pathway in a dose-dependent manner, limiting the malignant progression of pancreatic cancer (Fan et al., 2021). Here, STAT3 is linked to familial pancreatic carcinoma.