MAPK8 and gastric cancer: It inhibits the development of the human gastric cancer cells line SGC7901 by regulating the ribosomal protein-p53 signaling pathway and the Bcl-xl/Beclin-1 pathway (Mao et al., 2016), In addition, GF2 can also induce the apoptosis of gastric cancer cell SGC-7901 by causing the accumulation of ROS and activating the ASK-1/JNK signaling pathway (Mao et al., 2016).