Figure 2E represents the merged PPI network with green boxes illustrating the most crucial proteins in the network that signifies the hub/core targets of 18α-GA effective against NSCLC. The 6 core hub proteins identified as therapeutic targets were; EGFR, IGF1, MAPK1, AKT1, PIK3R1, and SRC (Figure 2F). The gene discussed is AKT1; the disease is non-small cell lung carcinoma.