The results of KEGG analysis revealed that the highly enriched top pathways involved were the PI3K-Akt signaling pathway, ErbB (EGFR) signaling pathway, pathways in cancer, estrogen signaling pathway, and Ras signaling pathway, among other closely related cancer signaling pathways associated with targets of 18α-GA against NSCLC. The gene discussed is EGFR; the disease is cancer.