AKT gene mutations are uncommon, while AKT gene amplification and overexpression are widespread in malignancies such as gastric, colon, liver, thyroid, and ovarian tumors (Staal, 1987; Bellacosa et al., 1995; Cheng et al., 1996; Nakatani et al., 1999; Roy et al., 2002; Knobbe and Reifenberger, 2003; Xu et al., 2004; Altomare and Testa, 2005; Parsons et al., 2005; Carpten et al., 2007; Malanga et al., 2008; Mohamedali et al., 2008; Shoji et al., 2009; Zilberman et al., 2009; Askham et al., 2010; Mundi et al., 2016; Manning and Toker, 2017). The gene discussed is AKT1; the disease is ovarian neoplasm.