MAO-B is associated with neuronal apoptosis, cellular excitotoxicity and oxidative stress in neuropsychiatric diseases such as Parkinson’s disease (PD), Alzheimer’s disease (AD) and depression (Tong et al., 2017; Park et al., 2019; Wu X. et al., 2021). This evidence concerns the gene MAOB and early-onset autosomal dominant Alzheimer disease.