It was shown that the levels of acetate, propionate and butyrate in the intestine of PCOS patients were significantly lower compared to healthy women, and after 10 weeks of probiotic treatment of PCOS patients, the abundance of intestinal Lactobacillus was significantly increased, as well as intestinal SCFA levels, which promoted insulin secretion (Zhang J. et al., 2019). The gene discussed is INS; the disease is polycystic ovary syndrome.