1. Inflammation: CRP, IL-6 and TNF-α↓; 2. Insulin resistance indicators: FINS, FPG, HOMA-IR↓; 3. Intestinal barrier: DAO, D-lactic acid↓; 4. Lipid metabolism indicators: TC, TG↓, HDL-C↑. The gene discussed is IL6; the disease is Insulin resistance.