In the present study, we found that the level of plasma endotoxin was dramatically decreased in AF/CSO group compared to AF/CO group (Figure 5A), and the expressions of hepatic TLR4 and its adaptor protein-MYD88 was significantly decreased in AF/CSO group compared to AF/CO group (Figure 5B). The gene discussed is MYD88; the disease is atrial fibrillation.