The standard treatment for patients with CRC includes fluoropyrimidine, oxaliplatin, irinotecan, and anti-vascular endothelial growth factor (VEGF); an anti-epidermal growth factor receptor (EGFR) therapy is also used for Kirsten rat sarcoma viral oncogene homolog (KRAS) wild type CRC 5. The gene discussed is KRAS; the disease is colorectal carcinoma.