The percentage of Ki-67-protein-positive cells in the colon tissues of the AOM/DSS + Abx + Akk group was significantly increased compared to that of the AOM/DSS + Abx group (Figures 2A,E), indicating that the supplementation with A. municiphila after antibiotic pretreatment strongly exacerbated the proliferation of colon cancer cells. The gene discussed is MKI67; the disease is colonic neoplasm.