Among them, inflammatory signalling pathways (e.g., the inflammatory response, IFNγ response, tumour necrosis factor-alpha signalling via nuclear factor kappa-B, interleukin (IL) 6–Janus kinase (JAK)–signal transducer and activator of transcription (STAT) 3 signalling, IFNα response, and IL2–STAT5 signalling) were significantly upregulated in the high-CRS subgroup (Figures 5(e) and 5(f)). Here, IFNG is linked to congenital rubella syndrome.