Previous studies have shown that aerobic exercise inhibits [10, 16] and reverses the process of inflammation and airway remodeling in mouse models of asthma, being mediated by increased expression of the anti-inflammatory cytokines IL-10 and IL-1ra, with a reduction in proinflammatory Th2 cytokines, such as IL-4, IL-5, and IL-13, which plays a key role in the maintenance of chronic inflammation and airway remodeling [2, 3, 5]. The gene discussed is IL4; the disease is asthma.