EDN3 and posterior cortical atrophy: A total of 32 genes related to the prognosis of PCa RFS were analyzed using univariate Cox analysis, and a prognostic model based on 18 genes of LASSO regression was constructed: EZH2*0.46 + ELL3*−0.18 + APOC1*−0.04 + NME1*−0.22 + FAM222A*−0.60 + SLC43A1*−0.71 + GCNT1*−0.04 + FOXD1*0.17 + COL2A1*0.028 + GPX2*−0.11 + FOXQ1*0.08 + ID4*−0.32 + IER3*−0.17 + SGCE*−0.13 + ANO5*−0.25 + FBXO17*−0.03 + PNMA8A*0.49 + EDN3*−0.03 (Figs. 2A and 2B).