GBM: Glomerular basement membrane, ATI: Acute tubular injury, FSGS: Focal segmental glomerulosclerosis, ATN: Acute tubular necrosis, IgAN: IgA Nephropathy, AIN: Acute interstitial nephritis, MCD: Minimal change disease, MPO-ANCA: Myeloperoxidase anti-neutrophil cytoplasmic antibodies. The gene discussed is MPO; the disease is IgA glomerulonephritis.