The purpose of this study is (1) to look at the expression of Cyclin D1 in HGBL, (2) the frequency of cyclin D1 in a selected number of cases, and (3) to identify the co-expression of proteins involved in cyclin D1 with c-Myc, Bcl2, and Bcl6 in HGBL. This evidence concerns the gene BCL6 and high grade B-cell lymphoma.